Insomnia and Hyperparathyroidism: Understanding the Connection

By Dr. David Danish

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The physicians at SleepScriptMD.com have treated countless patients suffering from insomnia, many of whom have underlying medical conditions contributing to their sleep disturbances. One lesser-known cause of insomnia is primary hyperparathyroidism (PHPT)—a condition where overactive parathyroid glands produce excessive parathyroid hormone (PTH), leading to elevated calcium levels in the blood. This biochemical imbalance can result in numerous health issues, including fatigue, depression, cognitive impairment, and sleep disturbances.

Understanding the link between PHPT and insomnia can help patients and providers identify appropriate treatment strategies, whether through medical intervention, lifestyle modifications, or targeted sleep therapy.

This guide is for informational purposes only and not a substitute for medical advice. Any treatment—whether a supplement, medication, procedure, injection, therapy, or device—carries potential risks, especially when used in excess or by individuals with certain medical conditions or genetic predispositions. Always consult a qualified healthcare provider before starting any treatment.

How Parathyroidectomy Can Improve Sleep Disturbances

Recent research highlights the significant impact of parathyroidectomy (surgical removal of an overactive parathyroid gland) on sleep quality. A study published in the World Journal of Surgery examined sleep disturbances in patients diagnosed with PHPT and evaluated how surgery affected their insomnia symptoms[1].

Study Overview

The study followed 197 PHPT patients, with 115 completing pre- and post-surgical sleep quality assessments using the Insomnia Severity Index (ISI). Before surgery, 62.6% of patients experienced sleep difficulties, and 25.2% met clinical criteria for insomnia[1].

Reduction in Insomnia Severity

After parathyroidectomy, there was a significant improvement in sleep quality:

  • ISI scores dropped from 10.3 pre-surgery to 6.2 post-surgery
  • 68.7% of patients reported improved sleep
  • 72.4% of those with clinical insomnia pre-surgery had their symptoms resolved
  • Patients reported longer total sleep duration and fewer nighttime awakenings[1]

Biochemical and Demographic Considerations

The study found no significant correlation between demographic factors, biochemical profiles, or the presence of obstructive sleep apnea with the severity of insomnia. This suggests that hormonal imbalance correction itself plays a key role in improving sleep quality, rather than external factors[1].

Addressing Insomnia with SleepScriptMD.com

If you suffer from insomnia—whether due to hormonal imbalances, stress, or other medical conditions—SleepScriptMD.com offers comprehensive, physician-led treatment options designed to provide safe and effective relief.

Why Choose SleepScriptMD?

  • Board-Certified Physicians: Dr. Danish and Dr. Kelly have a combined 30+ years of experience treating sleep disorders.
  • Synchronous and AI-Assisted Asynchronous Care: Get personalized treatment plans with expert guidance or opt for convenient AI-assisted care.
  • Medication & Supplement Options: We offer safe, non-addictive medications and evidence-based supplement recommendations tailored to your sleep needs.
  • At-Home Sleep Testing: We provide access to advanced sleep diagnostics to identify underlying causes of insomnia.
  • CBT-I Sleep Coaching: Our network includes certified Cognitive Behavioral Therapy for Insomnia (CBT-I) sleep coaches to help you develop lasting, non-medication-based strategies for better sleep.

Get Started Today

If you’re struggling with insomnia and want a science-backed approach to better sleep, visit www.SleepScriptMD.com to learn more about our treatment options. Whether through medical management, behavioral therapy, or lifestyle interventions, we are here to help you reclaim restful nights.

References

  1. World Journal of Surgery Study on Hyperparathyroidism and Insomnia